Hana Spanielová

Hana Španielová holds an M.S. in Molecular Biology and Genetics and a Ph.D. in Biomedicine with a specialization in virology from Charles University in Prague. Her research career has focused on virology, nanotechnology, targeted drug delivery, and advanced diagnostic systems. As Coordinator of the Viral Nanotechnology Group, she investigated molecular mechanisms of polyomavirus infection and virion assembly, while developing polyomavirus-based virus-like particles (VLPs) for diagnostics, vaccine applications, and nanotechnology. Her work also involved engineering viral nanoparticles to target cancer-specific receptors through genetic modification and bioconjugation. Currently, as a Researcher at the Institute of Organic Chemistry and Biochemistry in Prague, she studies intracellular nanoparticle delivery and the use of cell-penetrating peptides to enhance gene and drug delivery. Her research also includes the development of nanoparticle-based systems for miRNA detection and the analysis of gold nanoclusters, contributing to the growing field of nanomedicine and precision therapeutics.